Geriatric Use

Consistent with the INVEGA TRINZA® Prescribing Information:

• Clinical studies of INVEGA TRINZA® did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
• This drug is known to be substantially excreted by the kidney and clearance is decreased in patients with renal impairment, who should be given reduced doses. Because elderly patients are more likely to have decreased renal function, monitor renal function and adjust dosage.