Dosage Adjustments

Consistent with the INVEGA TRINZA® Prescribing Information:

For Schizophrenia:

• The first dose of INVEGA TRINZA® may be administered up to 7 days before or after the monthly time point of the next scheduled INVEGA SUSTENNA® dose.
• INVEGA TRINZA® is to be used only after INVEGA SUSTENNA® has been established as adequate treatment for at least four months.
• Following the initial INVEGA TRINZA® dose, INVEGA TRINZA® should be administered every 3 months.
• If needed, dose adjustment can be made every 3 months in increments within the range of 273 mg to 819 mg based on individual patient tolerability and/or efficacy. Due to the long-acting nature of INVEGA TRINZA®, the patient’s response to an adjusted dose may not be apparent for several months.

For illustrative displays of this dosing scenario, please click the link below.

Transitioning a Patient to INVEGA TRINZA®.

Prescribing Information for RISPERDAL CONSTA®