Renal Impairment

Consistent with the INVEGA SUSTENNA® Prescribing Information:

• INVEGA SUSTENNA® has not been systematically studied in patients with renal impairment. For patients with mild renal impairment [creatinine clearance ≥ 50 mL/min to < 80 mL/min (Cockcroft-Gault Formula)], initiate INVEGA SUSTENNA® with a dose of 156 mg followed by 117 mg one week later. Administer both doses in the deltoid muscle. Thereafter, follow with monthly injections of 78 mg in either the deltoid or gluteal muscle, which can be adjusted within the range of 39 mg to 156 mg based on tolerability and/or efficacy. INVEGA SUSTENNA® is not recommended in patients with moderate or severe renal impairment (creatinine clearance < 50 mL/min).

For illustrative displays of this dosing scenario, please click the link(s) below.

Dosing in Mild Renal Impairment for Schizophrenia